A naive, bumbling veterinarian named Corky Romano the outcast son if a Mafia boss, is recruited by his family to infiltrate the FBI and steal any and all evidence that will put his cranky father named Francis A. "Pops" Romano in jail! But he's in way over his head when he's made out to be a super agent. It's a reputation must live up to as he tries to fake his way through one tough assignment after another while hunting for the elusive incriminating proof of his father's illegal activities.

On the day that Hurricane Katrina hits New Orleans, elderly Daisy Williams (nee Fuller) is on her deathbed in a New Orleans hospital. At her side is her adult daughter, Caroline. Daisy asks Caroline to read to her aloud the diary of Daisy's lifelong friend, Benjamin Button. Benjamin's diary recounts his entire extraordinary life, the primary unusual aspect of which was his aging backwards, being diagnosed with several aging diseases at birth and thus given little chance of survival, but who does...